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Genes, Caffeine, and You – Why Some Of Us Buzz Longer Than Others 

Writer's picture: lcherrierlcherrier

Ever drink a cup of coffee at 3 PM and feel like you can run a marathon at midnight? Meanwhile, your coworker downs an espresso at 10 PM and snores by 11 PM? Your caffeine story is written in your genes, and pharmacogenomics sheds light on this mystery.


The Curious Case of Caffeine Metabolism

The gene responsible here is CYP1A2, which regulates how your liver processes caffeine. According to a study on PubMed (PMID: 30913588), individuals with certain genetic variants process caffeine faster, while others slow it down. That’s why your 8 AM latte might still be partying in your system by dinner time.


What Can You Do with This Info?




Knowing how you metabolize caffeine isn’t just for avoiding bad sleep. It can also prevent heart-related issues for those with genetic predispositions to caffeine sensitivity. Imagine a simple gene test saving you from heart palpitations after your third coffee of the day! Science really comes through, huh?

Is your coffee habit in harmony with your genes? Time for some fascinating brew science!  

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